| Vitamin Additive: | Vitamin B3 |
|---|---|
| Chemical: | Stability |
| Property: | Solubility |
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I. Appearance Characteristics Niacinamide usually appears as a white to slightly yellow crystalline powder, odorless or nearly odorless, with a slightly bitter taste. Its crystal form is relatively fine and uniform, and the appearance texture is rather delicate. It has good stability in appearance, and under normal storage conditions, there are generally no obvious changes in color, form, etc.
II. Uses
(A) Uses in the Pharmaceutical Field
1. **Treatment of Niacin Deficiency Disorders**: Niacinamide is an active form of vitamin B3 and can be used in the human body to treat disorders caused by niacin deficiency such as pellagra. Patients with pellagra often suffer from symptoms such as dermatitis, diarrhea, and dementia. Niacinamide participates in various metabolic processes in the body, supplements the lacking niacin-related functions in the human body, and thus improves these symptoms to help restore good health.
2. **Adjunctive Treatment in Cardiovascular Diseases**: In the treatment of cardiovascular diseases, niacinamide can participate in the energy metabolism process of myocardial cells. As a component of coenzymes, it helps maintain the normal function of the myocardium. In some cases of cardiovascular diseases such as myocardial ischemia and arrhythmia, it can play an adjunctive treatment role to promote the recovery and improvement of myocardial function.
(B) Uses in the Cosmetic Field
1. **Whitening Effect**: Niacinamide is widely used in the cosmetic field, and one of its most prominent uses is to whiten the skin. It can inhibit the transfer of melanosomes from melanocytes to keratinocytes, reduce the deposition of melanin on the skin surface, and thus gradually make the skin fair and translucent, effectively improving problems such as uneven skin tone and dark spots.
2. **Improvement of Skin Barrier Function**: Niacinamide helps to enhance the skin's barrier function. It can promote the synthesis of intercellular lipids in the skin such as ceramides, increase the water content of the stratum corneum of the skin, make the skin tougher, and better resist the damage caused by external environmental factors such as ultraviolet rays and pollutants to the skin, reducing the occurrence of problems such as dry skin and sensitivity.
3. **Oil Control and Regulation of Sebum Secretion**: For people with oily skin, niacinamide has the function of regulating sebum secretion. It can affect the activity of sebaceous glands, appropriately reduce the amount of sebum secretion, make the sebum secretion of the skin tend to be balanced, and then reduce the occurrence of skin problems such as pore blockage and acne caused by excessive sebum.
(C) Uses in Other Fields
1. **Food Nutritional Fortifier**: In the food industry, niacinamide can be used as a nutritional fortifier. Since it is a form of vitamin B3 required by the human body, adding it to some foods such as cereal products and beverages can supplement the niacin that may be lacking in the daily diet of the human body, helping to maintain the normal energy metabolism and good health of the human body.
2. **Chemical Synthesis Intermediate**: In the chemical synthesis field, niacinamide can be used as an intermediate to participate in the synthesis of some compounds. For example, in the synthesis of certain drugs or other organic synthesis processes, the specific chemical structure and properties of niacinamide can be utilized to construct new compounds, providing an important raw material basis for the research and development and production of relevant chemical products. In conclusion, niacinamide has the characteristics of white to slightly yellow crystalline powder in appearance, and in terms of uses, it covers multiple fields such as pharmaceuticals, cosmetics, food, and chemical synthesis, playing important and diverse roles.
| Anatysis Item | Unit | Specification | Test Method | Result |
| Appearance Solubility Ultraviolet absorption Infrared Identification Assay Melting range Readily carbonizable substances Loss on Drying Residue on ignition Mercury* Lead Arsenic Cadmium* Total Plate Count* Yeast & Molds* E Coli* Salmonella* |
% °C % % ppm ppm ppm ppm cfu/g cfug cfug 125g |
White, crystalline powder Freely soluble in water and alcohol;soluble in glycerin 0.63-0.67 (A245/A262) Conform to standard spectrum 98.5-101.5 128-131 Not deeper than the Matching fluidA ≤0.5 ≤0.1 ≤0.1 ≤2.0 ≤1.0 ≤1.0 ≤103 ≤102 Ne0atle Negative |
Eyeballing Welghtvolume method UN IR HPLC Melting point apparatus Colorimetry Drying method Combustion method AFS AAS AFS AAS Plating Patng Plating Plating |
White crystalline powder Conform 0.66 Conform 100.0 130.5-131.0 Conform 0.02 0.05 <0.003 A0.1 <0.05 <10 Negative Negative |
| Conciusior: Complies with the requlrements of USP2021. | ||||
| NoteThe items marked with are for internal sampling Inspection, in which the results of hazardous elements are from the extermaf inspection report, and the results of other Items are from internal inspection. |
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